The route through Huelva province comes from Sevilla by Sierra Norte towards Sierra de Aracena. Meadows and Mediterranean forest in its pure state. It comes down through Andevalo area, and passes near the capital towards so American flavoured villages like Palos de la Frontera and Moguer, which the route goes through. On its way to the coast it rounds the Parque Natural de Donana and after crossing river Guadalquivir by barge it again comes into Sevilla province.

Guide Maps